Cancer Imaging with Ultrasound Probes

Overview

Ultrasound has long been used clinically as a versatile, relatively inexpensive imaging modality; however, it has suffered from limitations of spatial resolution and often a lack of specificity. This project focuses on the development of targeted agents, specifically microbubbles that can be attached to specific ligands and targeted nanodroplets that are activated when vapourized by exposure to an external ultrasound beam. Other elements of this project include preclinical evaluation and work to adapt the bubbles and droplets to make them suitable for human use and the simultaneous use of microbubble ultrasound contrast imaging and dynamic contrast MRI for breast cancer detection.

Lead Principal Investigator:

Dr. Peter Burns, Sunnybrook Research Institute

Principal Investigators:

Dr. Rajiv Chopra, Sunnybrook Health Sciences Centre
Dr. Aaron Fenster, Robarts Research Institute
Dr. David Goertz, Sunnybrook Health Sciences Centre
Dr. Naomi Matsuura, Sunnybrook Health Sciences Centre
Dr. Stuart Foster, Sunnybrook Health Sciences Centre