Research Ethics Boards (REBs) are a critical component of the research process to ensure high quality research and appropriate protection of patients participating in clinical trials. REBs are independent bodies constituted of medical, scientific and non-scientific members, whose responsibility is to ensure the protection of the rights, safety and well-being of human subjects involved in a trial.
The Ontario Cancer Research Ethics Board (OCREB) works in collaboration with Ontario Institutions to ensure that research involving human subjects meets the highest standards of scientific and ethical conduct.
OCREB is organized and operates according to the Tri-Council Policy Statement: Guidelines on Research Involving Human Subjects (TCPS); the International Conference on Harmonisation (ICH) Good Clinical Practice (GCP)Consolidated Guideline; Part C, Division 5 of the Food and Drug Regulations of Health Canada; and the provisions of the Ontario Personal Health Information Protection Act 2004 (PHIPA) and its applicable regulations.
The Ontario Cancer Research Ethics Board will strive to uphold and protect the following TCPS principles:
- Respect for human dignity;
- Respect for free and informed consent;
- Respect for vulnerable persons;
- Respect for privacy and confidentiality;
- Respect for justice and inclusiveness;
- Balancing harms and benefits.