Francis Ouellette

Associate Director, Informatics and Bio-computing and Principal Investigator

Research Description

The technology required for cancer research has become increasingly more complex over the past several years. Accordingly, the development of innovative solutions to handle the large and complicated datasets these new technologies generate has become an essential part of the cancer research process. OICR’s Informatics and Bio-computing Platform, led by Dr. Lincoln Stein, integrates and interprets this data, developing visualization tools to turn raw data into meaningful information for biologists, clinicians and trainees. Francis Ouellette will contribute to this platform by integrating new data types with other publicly available molecular data. Ouellette is also the Scientific Coordinator of the Canadian Bioinformatics Workshop series.

Contact Information

Telephone
+1 (416) 673 8511
Email
francis@oicr.on.ca
Mailing Address
Ontario Institute for Cancer Research
MaRS Centre, South Tower
101 College Street, Suite 800
Toronto, Ontario
Canada, M5G 0A3

Current

2011 - Associate Professor, Department of Cell and Systems Biology, University of Toronto.
2008 - Associate Editor, Database: The Journal of Biological Databases and Curation.
2007 - Associate Director, Informatics and Bio-computing and Principal Investigator, Ontario Institute for Cancer Research (OICR).
1998 - Scientific Coordinator, Canadian Bioinformatics Workshops series., Canadian Bioinformatics Workshops.

Background

2004 - 2007Associate Director, UBC/Simon Fraser University (SFU) Canadian Institutes for Health Research (CIHR) Bioinformatics Training Program for Health Research, Simon Fraser University (SFU).
2004 - 2007Director, UBC Bioinformatics Center (UBiC).
2004 - 2007Associate Professor in Medical Genetics, Faculty of Medicine, University of British Columbia.
2002 - 2007Associate Professor, UBC’s Michael Smith Laboratories.
2002 - 2007Associate Director, Genome BC Bioinformatics.
1998 - 2007Director, Bioinformatics core facility for the Centre for Molecular Medicine and Therapeutics (CMMT).
1993 - 1998GenBank coordinator, National Centre for Biotechnology Information, National Institute for Health Research.

Selected Bibliography

  • Zhang KX and Ouellette BFF. CAERUS: predicting CAncER oUtcomeS using relationship between protein structural information, protein networks, gene expression data, and mutation data. PLoS Comp Bio. 2011 March.
  • Brazas MD, Yamada JT and Ouellette BF. Providing web servers and training in Bioinformatics: 2010 update on the Bioinformatics Links Directory. Nucleic Acids Res. 2010 Jul;38(Web Server issue):W3-6. Epub 2010 Jun 11.
  • Zhang KX and Ouellette BFF. Pandora, a PAthway and Network DiscOveRy Approach based on common biological evidence. Bioinformatics. 2010 Feb 15;26(4):529-35.
  • Zhang KX and Ouellette BFF. GAIA: a gram-based interaction analysis tool--an approach for identifying interacting domains in yeast. BMC Bioinformatics. 2009 Jan 30;10 Suppl 1:S60.
  • Gaudet et al. Towards BioDBcore: a community-defined information specification for biological databases. Database (Oxford). 2011 Jan 4;11:baq027.

Journals

Research Projects

  • CAERUS

    Predicting CAncER oUtcomeS using relationship between protein structural information, protein networks, gene expression data, and mutation data.

  • GAIA

    A gram-based interaction analysis tool – an approach for identifying interacting domains in yeast.

  • genomePad

    A mobile UCSC Genome Browser for the iPhone/iPod Touch.

  • PANDORA

    A PAthway and Network DiscOveRy Approach based on common biological evidence.

Workshops

Public Lectures