Martin Yaffe

Co-Program Leader, Smarter Imaging Program

Research Description

Early diagnosis and detection of a tumour before it grows and spreads is critical in surviving cancer. In addition, it is important to obtain information that profiles the tumour to guide decisions regarding the most effective approach to treatment. Some of this prognostic information can be extracted directly from medical images.

OICR’s Smarter Imaging Program, co-led by Dr. Martin Yaffe and Dr. Aaron Fenster, aims to detect tumours as early as possible and to provide useful prognostic information, using advanced imaging and screening techniques that they develop. Through its partners, the Imaging Translation Platform and the OICR Commercialization Program, they move new cancer imaging tools from the laboratory to the clinic where patients can benefit from new research.

Contact Information

Telephone
+1 (416) 480 5715
Mailing Address
Sunnybrook Research Institute
S657 - 2075 Bayview Avenue
Toronto, Ontario
Canada, M4N 3M5
Additional Contacts
Yulia Yerofeyeva
Yulia Yerofeyeva, Project Manager, Ontario Institute for Cancer Research (OICR)
+1 (416) 480 4348
Jennifer Chen
+1 (416) 480 4678
Website
Centre for Imaging Technology Commercialization (CImTeC)

Current

2010 - Associate Centre Director, Centre for Imaging Technology Commercialization.
2007 - Co-Program Leader, Smarter Imaging Program, Ontario Institute for Cancer Research (OICR).
2007 - Co-Platform Leader, Imaging Translation Platform, Ontario Institute for Cancer Research (OICR).
1994 - Professor, Departments of Medical Imaging and Medical Biophysics, University of Toronto.
1990 - Consultant Physicist, Ontario Breast Screening Program.
1990 - Senior Scientist, Sunnybrook Research Institute (SRI).

Background

1987 - 1994Associate Professor, Departments of Radiology and Medical Biophysics, University of Toronto.
1983 - 1990Senior Scientist Physics Division, the Ontario Cancer Institute., University Health Network (UHN).
1978 - 1995Consultant Physicist, St. Michael's Hospital, Toronto.
1978 - 1988Consultant Physicist: National Cancer Institute of Canada, National Breast Screening Study, Ontario Breast Screening Program.
1978PhD, Medical Biophysics, University of Toronto.

Selected Bibliography

  • Pisano, ED, Gatsonis C, Hendrick E, Yaffe M, Baum JK, Acharyya S, Conant EF, Fajardo LL, Bassett L, D'Orsi C, Jong R, Rebner M. Diagnostic accuracy of digital versus film mammography for breast cancer screening - The results of the American College of Radiology Imaging Network (ACRIN) Digital Mammographic Imaging Screening Trial (DMIST). NEJM. 2005;353:1773-1783.
    • Boyd NF, Guo H, Martin LJ, Sun L, Stone J, Fishell E, Jong RA, Hislop G, Chiarelli A, Minkin S, Yaffe MJ. Mammographic Density, and Risk and Detection of Breast Cancer, NEJM. 2007;356(3):227-236.
      • Soliman H , Gunasekara A, Rycroft M, Zubovits J, Dent R, Spayne J, Yaffe M, Czarnota GJ. Functional Imaging of Neoadjuvant Chemotherapy Response in Women With Locally Advanced Breast Cancer Using Diffuse Optical Spectroscopy. Clinical Cancer Research 2010.
        • Clarke GM, Peressotti C, Holloway CMB, Zubovits JT, Liu K, Yaffe MJ. Development and evaluation of a robust algorithm for computer-assisted detection of sentinel lymph node micrometastases. Histopathology. Volume 59, (1) 116–128 2011.
          • Kirsh VA, Chiarelli AM, Edwards S, O’Malley FP, Shumak R, Yaffe MJ, Boyd NF. Tumor characteristics associated with mammographic detection of breast cancer in the Ontario Breast Screening Program. JNCI 103 (12) 942-950 2011.