Anita Bane

Overview

Dr. Anita Bane's research interests involve the identification and validation of prognostic and predictive tissue-based biomarkers for the optimal management of breast cancer patients.

Her research is focused on two key areas. First, she is investigating the utilization of molecular techniques to improve breast cancer classification and to elucidate mechanistic differences between prognostically different breast cancer groups. Second, she is working to better understand the clinical significance of breast cancer stem cells with regard to patient outcome and predicting response to alternate radiation schedules and chemotherapeutic regimens.

These approaches could ultimately provide better treatment options and increased quality of life for breast cancer patients.

Contact Information

Dr. Anita Bane

Telephone: 905-527-4322 ext. 42063

Affiliations

2009 - Clinician-Scientist II, Ontario Institute for Cancer Research (OICR).
2008 - Assistant Professor, Department of Pathology and Molecular Medicine, McMaster University.
2008 - Staff Pathologist, Juravinski Hospital.
2002 - 2007PhD, Molecular Biology and Cancer Genetic, University of Toronto.
2001 - 2007Pathology Fellow, Mount Sinai Hospital, Toronto.
1998 - 2001Resident and Lecturer in Pathology, Trinity College, Dublin, Ireland.
1997 - 2001Resident in Anatomic Pathology and Cytopathology, Trinity College, Dublin, Ireland.

Research Output

  • Mulligan AM, Pinnaduwage D, Bane A, Bulls SB, O’Malley FP, Andrulis IL
    CK8/18 Expression, The Basal Phenotype and Family History in Identifying BRCA1-Associated Breast Cancer
    • Cancer. (Accepted July 2010)
  • Bane AL, Pinnaduwage D, Bull SB, O’Malley FP, Andrulis IL
    Expression Profiling of Familial Breast Cancers Demonstrates Higher Expression of FGFR2 in BRCA2-associated Tumors
    • Breast Cancer Research & Treatment. 2009 Sep;117(1):183-91
  • Viloria-Petit AM, Erdemir T, Bane A, Pinnaduwage D, Roncari L, Bose R, Narimatsu M, Wong J, O’Malley F, Andrulis I, Kerbel RS, Wrana J
    The TGFβ-Par6 Polarity Pathway Controls Breast Cancer Invasion and Metastasis
    • Proceedings of the National Academy of Sciences. 2009 Aug 18;106(33):14028-33
  • Bane AL, Beck JC, Bleiweiss I, Buys SS, Catalano E, Daly MB, Giles G, Godwin AK, Hisbshoosh H, Hopper JL, John EM , Layfield L, Longacre T, Miron A, Senie R, Southey MC, West DW, Whittemore AS, Wu H, Andrulis IL, O’Malley FP
    BRCA2 Mutation-Associated Breast Cancers Exhibit a Distinguishing Phenotype Based on Morphology and Molecular Profiles from Tissue Microarrays
    • Am J Surg Pathol. 2007 Jan;31(1):121-8
  • Mastracci T, Tjan S, Bane AL, O’Malley FP, Andrulis IL
    E-cadherin alterations in atypical lobular hyperplasia and lobular carcinoma in situ of the breast
    • Mod Pathol. 2005 Jun;8(6):741-51