Martin Yaffe


Early diagnosis and detection of a tumour before it grows and spreads is critical in surviving cancer. In addition, it is important to obtain information that profiles the tumour to guide decisions regarding the most effective approach to treatment. Some of this prognostic information can be extracted directly from medical images.

OICR’s Smarter Imaging Program, co-led by Dr. Martin Yaffe and Dr. Aaron Fenster, aims to detect tumours as early as possible and to provide useful prognostic information, using advanced imaging and screening techniques that they develop. Through its partners, the Imaging Translation Program and the OICR Commercialization Program, they move new cancer imaging tools from the laboratory to the clinic where patients can benefit from new research.

Contact Information

Yulia Yerofeyeva

yulia [dot] yerofeyevaatsri [dot] utoronto [dot] ca

Telephone: 416-480-4348


2010 - Associate Centre Director, Centre for Imaging Technology Commercialization.
2007 - Co-Program Director, Smarter Imaging Program, Ontario Institute for Cancer Research (OICR).
2007 - Co-Program Director, Imaging Translation Program, Ontario Institute for Cancer Research (OICR).
1994 - Professor, Departments of Medical Imaging and Medical Biophysics, University of Toronto.
1990 - Consultant Physicist, Ontario Breast Screening Program.
1990 - Senior Scientist, Sunnybrook Research Institute (SRI).
1987 - 1994Associate Professor, Departments of Radiology and Medical Biophysics, University of Toronto.
1983 - 1990Senior Scientist Physics Division, the Ontario Cancer Institute., University Health Network.
1978 - 1995Consultant Physicist, St. Michael's Hospital, Toronto.
1978 - 1988Consultant Physicist: National Cancer Institute of Canada, National Breast Screening Study, Ontario Breast Screening Program.
1978PhD, Medical Biophysics, University of Toronto.

Research Output

  • Pisano, ED, Gatsonis C, Hendrick E, Yaffe M, Baum JK, Acharyya S, Conant EF, Fajardo LL, Bassett L, D'Orsi C, Jong R, Rebner M
    Diagnostic accuracy of digital versus film mammography for breast cancer screening - The results of the American College of Radiology Imaging Network (ACRIN) Digital Mammographic Imaging Screening Trial (DMIST)
    • NEJM. 2005;353:1773-1783
  • Boyd NF, Guo H, Martin LJ, Sun L, Stone J, Fishell E, Jong RA, Hislop G, Chiarelli A, Minkin S, Yaffe MJ
    Mammographic Density, and Risk and Detection of Breast Cancer
    • NEJM. 2007;356(3):227-236.
  • Soliman H , Gunasekara A, Rycroft M, Zubovits J, Dent R, Spayne J, Yaffe M, Czarnota GJ
    Functional Imaging of Neoadjuvant Chemotherapy Response in Women With Locally Advanced Breast Cancer Using Diffuse Optical Spectroscopy
    • Clinical Cancer Research 2010
  • Clarke GM, Peressotti C, Holloway CMB, Zubovits JT, Liu K, Yaffe MJ
    Development and evaluation of a robust algorithm for computer-assisted detection of sentinel lymph node micrometastases
    • Histopathology. Volume 59, (1) 116–128 2011
  • Kirsh VA, Chiarelli AM, Edwards S, O’Malley FP, Shumak R, Yaffe MJ, Boyd NF
    Tumor characteristics associated with mammographic detection of breast cancer in the Ontario Breast Screening Program
    • JNCI 103 (12) 942-950 2011