Philip Awadalla


Philip Awadalla, PhD, is a Senior Investigator at the Ontario Institute for Cancer Research, Professor of Population and Medical Genomics at the University of Toronto, and is a Principal Investigator of the Canadian Partnership for Tomorrow Project and biobank. He is also the Director of the Genome Canada, Canadian Data Integration Centre. Dr. Awadalla was trained at the University of Edinburgh, and his team focuses on the development of next-generation genomics approaches, model-based tools and population-based approaches to study mutation rates, genome biology, and cancer. His team’s research also focuses on systems and population genomics approaches to capture signals in population-based samples or families as well as tools to capture rare or de novo variants, potentially critical to disease phenotypes. Dr. Awadalla’s main research interests include identifying genetic determinants of blood disorders and cancers; and genomic epidemiology of age related disorders in population cohorts.


2015 - Professor, Department of Molecular Genetics, Faculty of Medicine, University of Toronto.
2015 - OICR Senior Principal Investigator and Director, Ontario Health Study, Ontario Institute for Cancer Research (OICR).
2015 - Principal Investigator and Director, Genome Canada Canadian Data Integration Centre.
2013 - Adjunct Professor, Faculty of Medicine, McGill University.
2009 - Associate Professor, Ste Justine Hospital Research Centre, Department of Pediatrics Faculty of Medicine, University of Montreal.
2009Executive Scientific Director and Principal Investigator, CARTaGENE, CHU-Ste Justine.
2009 - 2015Co-Principal Investigator, CARTaGENE, CHU-Ste Justine.
2007 - 2009Assistant Professor, Ste Justine Hospital Research Centre, Department of Pediatrics Faculty of Medicine, University of Montreal.
2001 - 2003Wellcome Trust International Travelling Research Fellow, University of Edinburgh and University of California Davis.
2000 - 2001National Science and Engineering Research Council Postdoctoral Fellow and Killam Postdoctoral Fellow, University of British Columbia.
1997 - 2001PhD, University of Edinburgh.

Research Output

  • Hussin JG, Hodgkinson A, Idaghdour Y, Grenier JC, Goulet JP, Gbeha E, Hip-Ki E, Awadalla P.
    Recombination affects accumulation of damaging and disease-associated mutations in human populations.
  • Hodgkinson A, Idaghdour Y, Gbeha E, Grenier JC, Hip-Ki E, Bruat V, Goulet JP, de Malliard T, Awadalla P.
    High-resolution genomic analysis of human mitochondrial RNA sequence variation.
    • Science. 2014 Apr 25;344(6182):413-5. doi: 10.1126/science.1251110.
  • Hussin J, Sinnett D, Casals F, Idaghdour Y, Bruat V, Saillour V, Healy J, Grenier JC, de Malliard T, Busche S, Spinella JF, Larivière M, Gibson G, Andersson A, Holmfeldt L, Ma J, Wei L, Zhang J, Andelfinger G, Downing JR, Mullighan CG, Awadalla P.
    Rare allelic forms of PRDM9 associated with childhood leukemogenesis.
    • Genome Research. 2013 Mar;23(3):419-30. doi: 10.1101/gr.144188.112.
  • Awadalla P, Boileau C, Payette Y, Idaghdour Y, Goulet JP, Knoppers B, Hamet P, Laberge C; CARTaGENE Project.
    Cohort profile of the CARTaGENE study: Quebec's population-based biobank for public health and personalized genomics.
    • Int J Epidemiol. 2013 Oct;42(5):1285-99. doi: 10.1093/ije/dys160. Epub 2012 Oct 15.
  • Conrad DF, Keebler JE, DePristo MA, Lindsay SJ, Zhang Y, Casals F, Idaghdour Y, Hartl CL, Torroja C, Garimella KV, Zilversmit M, Cartwright R, Rouleau GA, Daly M, Stone EA, Hurles ME, Awadalla P; 1000 Genomes Project.
    Variation in genome-wide mutation rates within and between human families.
    • Nature Genetics. 2011 Jun 12;43(7):712-4. doi: 10.1038/ng.862.