Tom Hudson

President and Scientific Director

Research Description

As President and Scientific Director of the Ontario Institute for Cancer Research (OICR), Dr. Tom Hudson M.D. is responsible for bringing together Ontario’s cancer researchers to build a global centre of excellence. Under his direction OICR has launched several large-scale programs including the Ontario Health Study, the Cancer Stem Cell Program, the Pancreatic Cancer Genome Project (which is part of the International Cancer Genome Consortium), the Terry Fox Research Institute/OICR Selective Therapies Program and High Impact Clinical Trials.

Dr. Hudson is internationally renowned for his work in genomics and human genome variation. Past positions include leadership roles as Director of the McGill University and Genome Quebec Innovation Centre and Assistant-Director of the Whitehead/MIT Center for Genome Research, where he led a team that generated physical and gene maps of the human and mouse genomes. Dr. Hudson has been a founding member of the International Haplotype Map Consortium, the Public Population Project in Genomics (P3G) and the International Cancer Genome Consortium.

Dr. Hudson's laboratory at OICR is involved in the study of genome variation that affects cancer predisposition, progression, and response to therapy. His main project focuses on the genetic architecture of loci associated with risk to colorectal cancer.

In 2007, Dr. Hudson was appointed as Professor in the Departments of Molecular Genetics and Medical Biophysics at the University of Toronto. Dr. Hudson is a fellow of the Royal Society of Canada, is editor-in-chief of the journal Human Genetics and is a member of the board of reviewing editors of the journal Science. He has co-authored over 230 peer-reviewed scientific publications.

Contact Information

Telephone
+1 (416) 673 6650
Mailing Address
Ontario Institute for Cancer Research MaRS Centre, South Tower
101 College Street, Suite 800
Toronto, Ontario
Canada, M5G 0A3
Additional Contacts
Ms. Jackie Peca
Jackie Peca, Executive Assistant to Dr. Thomas J. Hudson, Ontario Institute for Cancer Research (OICR)
+1 (416) 673 6631

Current

2011 - Member, Board of Directors, Centre for Imaging Technology Commercialization.
2010 - Chair, Scientific Advisory Board, Slim Initiative in Genomic Medicine.
2008 - Member, Board of Directors, Cancer Stem Cell Consortium.
2008 - Co-Founder and Member of the Executive Committee, International Cancer Genome Consortium (ICGC).
2008 - Member, Board of Directors , Centre for Probe Development and Commercialization (CPDC).
2007 - Professor, Dept. of Molecular Genetics and Microbiology and Dept. of Medical Biophysics, University of Toronto.
2006 - President and Scientific Director, Ontario Institute for Cancer Research (OICR).
2006 - Canadian Cancer Research Alliance: Member, Board Directors., Canadian Cancer Research Alliance.
2005 - Member, Scientific Advisory Board, HudsonAlpha Institute for Biotechnology.
2004 - Founder and Scientific Director, Public Population Project in Genomics (P3G).

Background

2009 - 2010Member, Scientific Advisory Board, Genomics Based Drug Discovery/Broad Institute.
2007 - 2008Member, Scientific Advisory Board, Structural Genomics Consortium (SGC).
2006 - 2011Member, Scientific Review Committee, STARR Cancer Foundation.
2006 - 2010Member, International Scientific Advisory Board, UK Biobank .
2005 - 2008Vice-Chair, Board of Directors, Genome Canada.
2003 - 2007Director, McGill University and Génome Québec Innovation Centre.
2002 - 2007Associate Professor, Depts. of Medicine and Human Genetics, McGill University.
2001 - 2005Associate Director, Canadian Genetic Diseases Network.
1999 - 2006Associate Physician, Division of Clinical Immunology, McGill University Health Centre, Montreal General Hospital.
1999 - 2002Director, Montreal Genome Centre., McGill University and Génome Québec Innovation Centre.
1997 - 2001Professor and Co-Director, Inter-University Institute for Population Research.
1996 - 2000Visiting Assistant Professor, Department of Biology, Massachusetts Institute of Technology.
1995 - 2001Assistant Director, Whitehead Institute for Biological Research/ MIT Center.
1991 - 1993Postdoctoral Fellow in the laboratory of Dr. David Housman at the Center for Cancer Research, Massachusetts Institute of Technology (MIT).
1991 - 1993Postdoctoral Fellow in the laboratory of Dr. Eric Lander , Whitehead Institute for Biomedical Research, MIT.
1990 - 1991Postdoctoral Fellow in the laboratory of Drs. Danuta Radzioch and Emil Skamene, McGill Centre for the Study of Host Resistance., McGill University.
1988 - 1990Resident in Clinical Immunology and Allergy, Montreal General Hospital, McGill University.
1985 - 1988Resident in Internal Medicine, Université de Montréal (Hotel-Dieu Hospital, 1985-1987; St. Luc Hospital, 1987-1988; Chief Resident in Internal Medicine, 1987-1988), Université de Montréal.
1985MD, Université de Montréal.

Selected Bibliography

  • Rajan S, Djambazian H, Chu Pham Dang H, Sladek R, Hudson TJ. The Living Microarray: a High-Throughput Platform for Measuring Transcription Dynamics in Single Cells. BMC Genomics. 2011; 12; 115.
    • Fortier I, Burton PR, Robson PJ, Ferretti V, Little J, L'heureux F, Deschênes M, Knoppers BM, Doiron D, Keers JC, Linksted P, Harris JR, Lachance G, Boileau C, Pedersen NL, Hamilton CM, Hveem K, Borugian MJ, Gallagher RP, McLaughlin J, Parker L, Potter JD, Gallacher J, Kaaks R, Liu B, Sprosen T, Vilain A, Atkinson SA, Rengifo A, Morton R, Metspalu A, Wichmann HE, Tremblay M, Chisholm RL, Garcia-Montero A, Hillege H, Litton JE, Palmer LJ, Perola M, Wolffenbuttel BH, Peltonen L, Hudson TJ. Quality, quantity and harmony: the DataSHaPER approach to integrating data across bioclinical studies. Int J Epidemiol. 2010; 39; 1383-93.
      • International Cancer Genome Consortium (Hudson TJ is lead and corresponding author). International network of cancer genome projects. Nature. 2010; 464; 993-8.
        • Toronto International Data Release Workshop Authors, (Hudson TJ is co-lead and corresponding author with Birney E.). Prepublication data sharing. Nature. 2009; 461; 168-70
          • International HapMap Consortium, (TJ Hudson is Project Leader of the Canadian Group). A Haplotype Map of the Human Genome. Nature. 2005; 437:1299-1320.
            • Zanke BW, Greenwood C MT, Rangre J, Kustra R, Tenesa A, Farrington SM, Prendergast J, Olschwang S, Chiang T, Crowdy E, Ferretti V, Laflamme P, Sundararajan S, Roumy S, Olivier J, Robidoux F, Sladek R, Montpetit A, Campbell P, Bezieau S, O’Shea AM, Zogopoulos G, Cotterchio M, Newcomb P, McLaughlin J, Younghusband B, Green R, Green J, Porteous MEM, Campbell H, Blanche H, Sahbatou M, Tubacher E, Bonaiti-Pellié C, Buecher B, Riboli E, Kury S, Chanock S, Potter J, Thomas G, Gallinger S, Hudson T, Dunlop MG. A Colorectal Cancer Susceptibility Locus on Chromosome 8q24 Identified by a Genome-Wide Association Scan. Nature Genetics. 2007; 39: 989 – 994.
              • Pastinen T, Hudson TJ. Cis-Acting Regulatory Variation in the Human Genome. Science. 2004; 306: 647-650.
                • Daly MJ, Rioux JD, Schaffner SF, Hudson TJ, Lander ES. High-resolution haplotype structure in the human genome. Nature Genetics. 2001; 29: 229-232.
                  • Hudson TJ, Stein L, Gerety S, Ma J, Castle A, Silva J, Slonim D, Baptista R, Rosenberg C, Reeve-Daly MP, Rozen S, Hui L, Hu X, Xu S-H, Wu X, Vestergaard C, Wilson K, Bay J, Colbert A, Maitra S, Ganiatsis S, Evans C, Ingalls K, Nahf R, Kruglyak L, Anderson M, Collymore A, Courtney D, Devine R, Horton L, Kouyoumjian V, Nguyen H, Renaud M, Tam J, Ye WJ, Zemsteva I, O'Connor T, Faure S, Fizames C, Goodman N, Weissenbach J, Hawkins T, Foote S, Page DC, Lander ES. An STS-based map of the human genome. Science. 1995; 270: 1945-1954.