Dr. Harriet Feilotter

Associate, Diagnostic Development

Dr. Harriet Feilotter’s research focuses on the implementation of biomarkers to be used in the screening, diagnosis or treatment of human diseases, including cancer. Using her dual role as a researcher in Pathology and Molecular Medicine, and service chief of laboratory genetics at the Kingston Health Sciences Center, her research is geared towards clinical applications of targeted biomarkers.

Her research includes the study of DNA, RNA and protein biomarkers in a variety of diseases including breast, lung, melanoma, bladder and colon cancers. The Feilotter Lab makes use of multiple platforms, including massively parallel sequencing, to generate and validate targeted biomarker data. Her primary focus is in developing and standardizing pathways for the effective implementation of robustly evaluated biomarkers in the clinical setting, including the assessment of quality metrics.  To that end, she engages in community ring studies to assess methodology for evaluation of analytic parameters for targeted molecular assays. Due to the networked nature of the work, she also has an interest and focus in informatics, including the proper handling, storage and sharing of biomarker data, the preprocessing pipelines required to ensure high quality data, the analytic pipelines needed to deliver an effective clinical tool and the ability to federate multiple types of data into formats suitable for sharing, querying and storing.

Current affiliations

  • Associate, OICR Diagnostic Development, OICR
  • Chief Scientific Officer and member, Indoc Research
  • Professor, Dept. of Pathology and Molecular Medicine, Queen’s University
  • Service Chief, Division of Laboratory Genetics, Kingston Health Sciences Center
  • Director, Molecular Genetics Laboratory, Kingston Health Sciences Center
  • Associate Member, Cancer Research Institute, Queen’s University
  • Chair, Molecular Oncology Advisory Committee, Cancer Care Ontario

Research interests

  • Diagnostic development
  • Targeted biomarkers
  • Genetics
  • Molecular pathology
  • Informatics
  • Quality metrics

Select publications

See Dr. Feilotter’s recent publications on PubMed.

Awards

  • Ontario Brain Institute, Top Achievement, 2017
  • Women in Cancer Research International Women’s Day write-up, 2017
  • The Pathologist, Cover Story, 2017
  • Canadians for Health Research, Researcher of the Month, 2016

Previous experience and education

  • Genetics Consultant, St. Michael’s Hospital, Toronto
  • Acting Clinical Chief, Genetics, Laboratory Medicine, Eastern Health, Newfoundland
  • Assistant/Associate Professor, Dept. of Pathology and Molecular Medicine, Queen’s University
  • CCMG Fellow, Kingston General Hospital
  • Post doctoral research fellow, Cold Spring Harbor Laboratory
  • PhD research, Dept. of Microbiology, University of Oxford
  • PhD candidate, Dept. of Biology, Queen’s University
  • M.Sc. candidate, Dept. of Biology, Queen’s University

Opportunities to collaborate

To collaborate with Dr. Feilotter, please contact her directly. Visit OICR’s Collaborative Research Resources directory for more opportunities to collaborate with OICR researchers.

Related links

Queen’s University Cancer Research Institute Member profile – Dr. Harriet Feilotter

OMPRN Researcher Profile – Dr. Harriet Feilotter

Contact

Dr. Harriet Feilotter
hf4@queensu.ca