Dr. Ken Aldape
Dr. Ken Aldape is a neuropathologist and laboratory scientist with research interests in brain tumours and cancer genomics in general. While department chair of pathology at MD Anderson Cancer Center, he prioritized investigational work to translate improvements in diagnosis and outcome, including the integration of next generation sequencing technology in the clinic. He is a neuropathology consultant, and a key reviewer of national and international glioma clinical trials. He is a participant in the World Health Organization panel developing updated guidelines for the classification of brain tumours and spearheads the integration of molecular information in pathology. He is a member of the Ontario Molecular Pathology Research Network (OMPRN), with a mandate to enhance research capacity, collaboration and leadership in cancer pathology at cancer centres in Ontario.
- Associate, OICR
- Member, Steering Committee, Ontario Molecular Pathology Research Network
- Neuropathologist, Senior Scientist, Princess Margaret Cancer Centre
- Director of MacFeeters-Hamilton Neuro-oncology Program
- Professor, Laboratory Medicine and Pathobiology, University of Toronto
- Cancer genetics
- Genomics and proteomics
- Clinical trials
- Brain cancer
- Agnihotri S, Jalali S, Wilson M, …, Aldape KD, Zadeh G. The genomic landscape of schwannoma. Nat Genet. 2016; 48(11):1339-1348.
- Bhat KP, Balasubramaniyan V, Vaillant B, …, Aldape K. Mesenchymal differentiation mediated by NFκB promotes radiation resistance in glioblastoma. Cancer Cell.2013; 24(3):331-46.
- Noushmehr H, Weisenberger DJ, Diefes K, …, Aldape K, Cancer Genome Atlas Research Network. Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma. Cancer Cell. 2010; 17(5):510-22.
- Olar A, Wani KM, Alfaro-Munoz KD, …, Aldape KD. IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II-III diffuse gliomas. Acta Neuropathol. 2015; 129(4):585-96.
- Phillips HS, Kharbanda S, Chen R, …, Aldape K. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006;9(3):157-73.
See Dr. Aldape’s recent publications on PubMed.
- Web of Science Citation Index, H-index of 92, 2015
- Society for Neuro-Oncology, Guha Award for Excellence in Neuro-Oncology Research
- Society for Neuro-Oncology, Levin Award for Contributions to Neuro-Oncology Research
- Society for Neuro-Oncology Annual Meeting, Translational Research Award
- Best Doctors, Best Doctors in America, 2005
Previous experience and education
- Senior Scientist, Princess Margaret Cancer Centre
- Director, MacFeeters-Hamilton Centre for Neuro-Oncology Research
- Section Chief, Neuropathology, Toronto General Hospital
- Director, Translational Genomics Laboratory, OICR
Opportunities to collaborate
For opportunities to collaborate with Dr. Aldape, please contact him directly.
Visit OICR’s Collaborative Research Resources directory for more opportunities to collaborate with OICR researchers.
Dr. Ken Aldape