The overall goal of Dr. Jones’ research is to identify, characterize, and target metabolic vulnerabilities of leukemic stem cells in order to improve outcomes for patients with leukemia. To achieve this goal her lab uses primary leukemia specimens, patient-derived xenograft models, as well as mass spectrometry-based metabolomic and lipidomic analysis. The ultimate objective of the lab is to translate laboratory findings into the clinic and understand clinical observations through laboratory studies.