Programs and initiatives

The following programs and initiatives are built to realize the Institute’s ambitious plans and to ensure OICR’s research will be translated to results for patients. To better understand how these programs and initiatives fit together, read about our strategy here.

Jump to: Technology Programs | Translational Research Initiatives | Global Leadership in Precision Oncology
| Collaborative Research Networks | Programs from the 2010-2015 Strategic Plan

Technology Programs

Diagnostic Development

The Diagnostic Development Program's mission is to initiate, disseminate and nurture expertise in the development of diagnostic assays and support the rapid implementation of precision medicine.

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Drug Discovery

The Drug Discovery Program helps efficiently translate discoveries made in Ontario’s labs into novel oncology therapies.

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Genomics

The Genomics Program provides large-scale, next generation sequencing cancer genomics capabilities to researchers in Ontario and beyond.

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Imaging

The Imaging Program accelerates translation of research findings and developments of new imaging techniques and probes of cancer into clinical practice.

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Informatics

The Informatics Program develops new algorithms, software, databases, visualization tools and other necessary components to interpret the large and complex datasets being generated by OICR’s cancer research programs.

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Translational Research Initiatives

Acute Leukemia

The goal of the Acute Leukemia TRI is to improve outcomes for patients by developing new biomarkers that can be used to better predict how patients will respond to therapy.

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Brain cancer

The goal of the Brain Cancer TRI is to investigate the cellular and genetic differences (heterogeneity) of Medulloblastoma (MB) and Glioblastoma Multiforme (GBM) in children and adults.

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Immuno-oncology

The goal of the Immuno-oncology TRI is to develop and clinically test an OICR-supported oncolytic virus treatment in combination with two cutting-edge immunotherapy strategies in order to improve outcomes for cancer patients, specifically for those with advanced metastatic cancers.

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Ovarian Cancer

The goal of the Ovarian Cancer TRI is to better understand how ovarian cancer develops, what causes resistance to current therapy and how ovarian cancer can be better targeted with new therapies.

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PanCuRx

PanCuRx seeks solutions to the high fatality rate of pancreatic cancer by generating new knowledge about genetic and biologic subsets of disease, mechanisms of tumorigenesis and tailored treatment options.

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Global Leadership in Precision Oncology

Global Alliance for Genomics and Health

The Global Alliance for Genomics and Health (GA4GH) was formed to help accelerate the potential of genomic medicine to advance human health.

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International Cancer Genome Consortium / International Cancer Genome Consortium for Medicine

The goal of the ICGC is to generate comprehensive catalogues of genomic abnormalities in tumours from 50 different cancer types.

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OCTANE

Ontario-wide Cancer TArgeted Nucleic acid Evaluation (OCTANE) is a new OICR-supported initiative that provides next generation sequencing-based molecular profiling at multiple Ontario cancer centres.

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Translational Genomics Laboratory

The Transformative Genomics Laboratory was built to fulfill an unmet need and further the use of genomics technologies in the clinical oncology space.

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Collaborative Research Networks

Health Services Research Network

The Health Services Research Network provides the knowledge needed to optimize the delivery of cancer services today and to ensure appropriate dissemination of health service innovations and well-evaluated technologies

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Ontario Molecular Pathology Research Network

The Ontario Molecular Pathology Research Network is a province-wide network of pathologists collaborating to carry out high-quality cancer research with a clear potential for clinical impact.

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Ontario Tumour Bank

The Ontario Tumour Bank is a province-wide biorepository and data bank focused on collection of tumour-related human biospecimens.

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Ontario Health Study

The Ontario Health Study is a landmark study with over 230,000 participants that will help researchers better understand the environmental, lifestyle, and genetic factors that cause cancer and other chronic diseases.

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Canadian Cancer Clinical Trials Network

The Canadian Cancer Clinical Trials Network is a pan-Canadian initiative to improve the efficiency and quality of clinical trials in Canada.

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Ontario Cancer Research Ethics Board

The Ontario Cancer Research Ethics Board is an expert central oncology REB serving almost every hospital in Ontario that conducts cancer clinical trials.

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Programs from the 2010-2015 Strategic Plan

Cancer Stem Cell

The Cancer Stem Cell Program is determining whether cancer stem cells are clinically relevant by expanding the knowledge of tumour-initiating cells in several types of cancer.

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ORBiT

The Ontario Regional BioTherapeutics (ORBiT) Program's mandate is to coordinate and drive the clinical testing and translation of promising anti-cancer biotherapies.

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Innovation in Target Validation

The Innovation in Target Validation Program is developing and deploying innovative technologies in aid of cancer target discovery and validation.

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