Cancer Therapeutics Innovation Pipeline – Request for applications

The Cancer Therapeutics Innovation Pipeline (CTIP) Program was established to capitalize on Ontario’s expertise in cancer biology and drug discovery. Its aim is to create a pipeline of validated cancer targets and first-in-class or best-in-class, novel, selective lead molecules (small molecules or biologics) that will attract partnerships and/or investment for further preclinical and clinical development. To generate a sustainable pipeline, CTIP will support projects that aim to provide increasing evidence of target validation and disease association using data from knowledge bases, functional assays, and drug screening in relevant in vitro and in vivo models of the cancer type of interest.

WOO Network Call for Concepts

The Ontario Institute for Cancer Research (OICR) Window-of-Opportunity (WOO) Network is inviting concept submissions for WOO trials, which exploit the ‘window’ of time after cancer diagnosis, typically prior to initiation of cancer therapy (usually surgery with curative intent). In presurgical WOO trials, patients with treatment naïve or early-stage disease are treated for a brief ‘window’ period with a novel therapy followed by surgical resection.

Funding support is provided to prioritized trial concepts that meet funding criteria. Investigators will present their concepts during the WOO Network Meeting on Thursday, February 9, 2023. Once prioritized, further trial development is engaged, facilitated and iterative.