close

Join our Mailing List

Receive the latest news, event invites, funding opportunities and more from the Ontario Institute for Cancer Research.

Research > Researchers
Dr. Sagi Abelson
Dr. Sagi Abelson
Contact
Dr. Sagi Abelson
Mid-Career Investigator

SAbelson@oicr.on.ca

Mid-Career Investigator

Dr. Sagi Abelson’s work aims to understand the extrinsic selective pressures and cell-intrinsic mechanisms governing clonal dominance and cell transformation in healthy tissues and cancer-prone diseases.

External Links

Better identification and characterization of the programs that lead to cancer will provide opportunities for early cancer detection and prevention. Dr. Abelson’s work focuses on the analysis of genomics and other age-related quantitative factors to understanding the aetiology of cancer for the purpose of risk estimation. To improve patient care and outcome, the team seek to develop and bring advanced sequencing methodologies and bioinformatics tools into clinical use.

Current Affiliations
  • Mid-Career Investigator, OICR
  • Assistant Professor, Department of Molecular Genetics, University of Toronto
Select Publications
  • Blood-based epigenetic instability linked to human aging and disease.
    Basrai S, Nofech-Mozes I, Detroja R…Abelson S.
    Nat Commun. 2026 Feb 14. doi: 10.1038/s41467-026-69430-z. Online ahead of print.PMID: 41690920
  • Pan-cancer classification of single cells in the tumour microenvironment.
    Nofech-Mozes I, Soave D, Awadalla P, Abelson S.
    Nat Commun. 2023 Mar 23;14(1):1615. doi: 10.1038/s41467-023-37353-8.PMID: 36959212
  • Clinical significance of clonal hematopoiesis in the setting of autologous stem cell transplantation for lymphoma.
    Lackraj T, Ben Barouch S, Medeiros JJF…Abelson S, Kridel R.Am
    J Hematol. 2022 Dec;97(12):1538-1547. doi: 10.1002/ajh.26726. Epub 2022 Sep 26.PMID: 36087071
  • Clonal haematopoiesis is associated with higher mortality in patients with cardiogenic shock.
    Scolari FL, Abelson S, Brahmbhatt DH,…Billia F.
    Eur J Heart Fail. 2022 Sep;24(9):1573-1582. doi: 10.1002/ejhf.2588. Epub 2022 Jul 10.PMID: 35729851
  • SmMIP-tools: a computational toolset for processing and analysis of single-molecule molecular inversion probes-derived data.
    Medeiros JJF, Capo-Chichi JM, Shlush LI…Abelson S.
    Bioinformatics. 2022 Apr 12;38(8):2088-2095. doi: 10.1093/bioinformatics/btac081.PMID: 35150236
  • Integration of intra-sample contextual error modeling for improved detection of somatic mutations from deep sequencing.
    Abelson S, Zeng AGX, Nofech-Mozes I…Bratman SV.
    Sci Adv. 2020 Dec 9;6(50):eabe3722. doi: 10.1126/sciadv.abe3722. Print 2020 Dec.PMID: 33298453
  • Prediction of acute myeloid leukaemia risk in healthy individuals.
    Abelson S, Collord G, Ng SWK… Shlush LI.
    Nature. 2018 Jul;559(7714):400-404. doi: 10.1038/s41586-018-0317-6. Epub 2018 Jul 9.PMID: 29988082
  • Tracing the origins of relapse in acute myeloid leukaemia to stem cells.
    Shlush LI, Mitchell A, Heisler L, Abelson S…Dick JE.
    Nature. 2017 Jul 6;547(7661):104-108. doi: 10.1038/nature22993. Epub 2017 Jun 28.PMID: 28658204

See Dr. Abelson’s recent publications on PubMed.

Research Areas
Aging Cancer Computational Biology Early Detection and Diagnosis Epigenetics Genomics Transcriptomics
Disease Areas
Age-related chronic diseases Clonal hematopoiesis Hematological cancer Solid cancers
Opportunities to Collaborate
Collaborate with us

To collaborate with Dr. Abelson, please contact him directly.

Visit OICR’s Collaborative Research Resources directory for more opportunities to collaborate with OICR researchers.

Programs
Computational Biology
Utilizes datasets from multiple sources for the development and application of algorithms for cancer genome analysis, biomarker discovery, cancer pathway discovery, data integration and tumour evolution research.
Learn More