Dr. Anna Panchenko

Senior Investigator

Dr. Anna Panchenko’s research group studies the genetic and epigenetic mechanisms of cancer, including the effects of mutations on protein activity, interactions and dynamics. To do so, her group designs new computational methods and algorithms that involve machine learning, molecular modeling and molecular dynamics simulations. Dr. Panchenko’s methods have been widely used by thousands of scientists from around the world.

Dr. Panchenko is particularly interested in discovering cancer-driving mutations with computational and hybrid approaches so that we can better understand – and potentially stop – the causes of cancer progression.

Dr. Panchenko is a Professor in the Faculty of Health Sciences at Queen’s University and an OICR Senior Investigator. She holds a Tier I Canada Research Chair.

Current affiliations

  • Senior Investigator, OICR
  • Professor, Faculty of Health Sciences, Queen’s University
  • Canada Research Chair, Tier I

Research interests

  • Protein structure and function
  • Chromatin and nucleosome dynamics
  • Epigenetics of carcinogenesis
  • Cancer mutagenesis

Select publications

See Dr. Panchenko’s recent publications on PubMed or on Google Scholar.

Select tools

  • HYDROID: Hydroxyl-radical footprint gel electrophoresis image
    analysis and interpretation
  • MutaGene: Identifies and explores context-dependent mutational
    processes in cancer
  • MutaBind: Estimates effects of sequence variants on protein
    interactions

Editorial boards

  • Associate Editor, PloS Computational Biology
  • Editor, Journal of Molecular Biology

Previous experience and education

  • Lead Scientist, National Center for Biotechnology Information (NCBI), National Institutes of Health (NIH)
  • Associate Investigator, NCBI, NIH
  • Staff Scientist, NCBI, NIH
  • Associate Professor Lecturer, Johns Hopkins University
  • Associate Professor Lecturer, George Washington University
  • Intramural Research Training Award Fellow, NCBI, NIH
  • Postdoctoral Fellow, University of Illinois at Urbana-Champaign
  • PhD, Lomonosov Moscow State University

Opportunities to collaborate

If interested in collaborating with Dr. Panchenko, please contact her directly.

Visit OICR’s Collaborative Research Resources directory for more opportunities to collaborate with OICR researchers.

Related links

Contact

Dr. Anna Panchenko
anna.panchenko@queensu.ca