Dr. Hartland Jackson

Investigator I

The coordinated activity of many individual cells is necessary for the function of healthy tissues but can also drive cancer progression. Dr. Jackson’s research program investigates the locations and relationships between different cell types, their mechanisms of communication, and their use as high-dimension pathology biomarkers of disease in clinical samples. He aims to understand the formation and evolution of tissues and tumours as multi-cell systems.

Dr. Jackson is a leader in imaging mass cytometry and is the most experienced user of the Hyperion Imaging System worldwide. He developed the histoCAT computational toolbox for interactively investigating highly multiplex imaging mass cytometry data and has applied these methods to quantify the cellular architecture of breast cancer. He is now extending this approach to other cancers and complementary mouse model systems in order to identify and target multi-cellular mechanisms of cancer progression and therapeutic resistance.

Dr. Jackson is an Investigator at Sinai Health’s Lunenfeld-Tanenbaum Research Institute.

Current affiliations

  • Investigator I, OICR
  • Investigator, Lunenfeld-Tanenbaum Research Institute, Sinai Health

Research interests

  • Single cell systems pathology
  • Imaging mass cytometry
  • Quantitative digital pathology
  • Systems biology
  • Breast cancer
  • Tumour heterogeneity
  • Tumour microenvironment

Select publications

*Authors contributed equally.

See all of Dr. Jackson’s publications on PubMed or on Google Scholar.

Awards

  • Cancer Research Society Scholarship for the Next Generation of Scientists, 2018
  • Canadian Institute of Health Research Post-Doctoral Fellowship, 2016
  • SystemsX Transitional Post-Doctoral Fellowship, 2015
  • European Molecular Biology Organization Long-Term Fellowship, 2015

Previous experience

  • Postdoctoral Fellow, University of Zurich
  • PhD, Princess Margaret Cancer Centre, University of Toronto

Related links

Lunenfeld Tanenbaum Research Institute – Hartland Jackson

Opportunities to collaborate

To collaborate with Dr. Jackson, please contact him directly.

Visit OICR’s Collaborative Research Resources directory for more opportunities to collaborate with OICR researchers.

Contact

Dr. Hartland Jackson
hjackson@lunenfeld.ca