Dr. Philippe Bedard

Co-Principal Investigator, OCTANE

Dr. Philippe Bedard is the Co-Principal Investigator of the OICR-supported Ontario-wide Cancer TArgeted Nucleic Acid Evaluation (OCTANE) study. He is a Medical Oncologist at the Princess Margaret Cancer Centre, where he treats patients with breast and testicular cancers while researching new ways to detect and treat these diseases.

Dr. Bedard’s research interests include the use of prognostic gene expression profiles in early-stage breast cancer, neoadjuvant breast cancer clinical trials, and early drug development. He is the principal investigator for ongoing phase I and phase II clinical trials that include patients with breast cancer and other advanced solid malignancies.

Current affiliations

Co-Principal Investigator, Ontario-wide Cancer TArgeted Nucleic Acid Evaluation (OCTANE) study
Staff Medical Oncologist, Princess Margaret Cancer Centre
Associate Professor of Medicine, University of Toronto

Research interests

Breast cancer
Cancer of the urinary system
Clinical genomics
Clinical trial design
New drug development
Phase 1 trials
Prognostic markers

Select publications

Stockley T, Oza A, Berman H, …, Bedard P. Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial. Genome Med. 2016; 8(1):109.
Srikanthan A, Tran B, Beausoleil M, …, Bedard P. Large Retroperitoneal Lymphadenopathy As a Predictor of Venous Thromboembolism in Patients With Disseminated Germ Cell Tumors Treated With Chemotherapy. J Clin Oncol. 2015; 33(6):582-587.
Bedard P, Tabernero J, Janku F, …, Sessa, C. A Phase Ib Dose-Escalation Study of the Oral Pan-PI3K Inhibitor Buparlisib (BKM120) in Combination with the Oral MEK1/2 Inhibitor Trametinib (GSK1120212) in Patients with Selected Advanced Solid Tumors. Clin Cancer Res. 2015; 21(4):730-8.
Bedard PL, Hansen AR, Ratain MJ, Siu LL. Tumour heterogeneity in the clinic. Nature. 2013; 501(7467):355-64.

See Dr. Bedard’s recent publications on PubMed or on Google Scholar.

Awards

Canadian Cancer Society Research Institute, William E. Rawls Prize, 2017
University of Toronto, Department of Medicine, Individual teaching Excellence Award, 2014
Conquer Cancer Foundation, Career Development Award, 2012-2014
National Institutes of Health, NCI-CTEP National Institutes of Health Cancer Therapy Evaluation Program, Career Development Award, 2010-2011
American Association for Cancer Research, AACR Translational Research Scholars Award, 2009

Previous experience

MD, University of Toronto

Opportunities to collaborate

To collaborate with Dr. Bedard, please contact him directly.

Visit OICR’s Collaborative Research Resources directory for more opportunities to collaborate with OICR researchers.

Contact

Dr. Philippe Bedard
Philippe.Bedard@uhn.ca

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