Dr. Hartland Jackson
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The coordinated activity of many individual cells is necessary for the function of healthy tissues but can also drive cancer progression. Dr. Jackson’s research program investigates the locations and relationships between different cell types, their mechanisms of communication, and their use as high-dimension pathology biomarkers of disease in clinical samples. He aims to understand the formation and evolution of tissues and tumours as multi-cell systems.
Dr. Jackson is a leader in imaging mass cytometry and is the most experienced user of the Hyperion Imaging System worldwide. He developed the histoCAT computational toolbox for interactively investigating highly multiplex imaging mass cytometry data and has applied these methods to quantify the cellular architecture of breast cancer. He is now extending this approach to other cancers and complementary mouse model systems in order to identify and target multi-cellular mechanisms of cancer progression and therapeutic resistance.
Dr. Jackson is an Investigator at Sinai Health’s Lunenfeld-Tanenbaum Research Institute.
*Authors contributed equally.
See all of Dr. Jackson’s publications on PubMed or on Google Scholar.
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