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TechnologyTreatment

New treatment for recurrent pediatric brain cancer enters clinical testing

OICR-supported study helps move promising CAR-T cell therapy into a first-in-child clinical trial Recurrent brain tumours are some of the most difficult cancers to treat, with no approved targeted therapies available and only a few…

ArticleMay 06, 2020

TechnologyTreatment

Study shows common cell protein could be targeted to treat childhood brain cancers

Researchers discover that childhood brain cancer could be treated by blocking key cell-surface protein, pointing to a potential treatment approach with fewer toxic side effects Chemotherapy for children with brain cancer is often toxic, leaving…

ArticleFeb 25, 2020

TechnologyMultiple cancers

Researchers discover a new cancer-driving mutation in the “dark matter” of the cancer genome

Change in just one letter of DNA code in a gene conserved through generations of evolution can cause multiple types of cancer Toronto – (October 9, 2019) An Ontario-led research group has discovered a novel…

ArticleOct 09, 2019

TechnologyTreatment

New research unfolds the DNA “origami” behind brain cancers

Collaborative research group maps the three-dimensional genomic structure of glioblastoma and discovers a new therapeutic strategy to eliminate cells at the roots of these brain tumours Current treatment for glioblastoma – the most common type…

ArticleJul 17, 2019

TechnologyBrain cancer

The unanticipated early origins of childhood brain cancer

Study identifies earliest traces of brain cancer long before the disease becomes symptomatic Toronto (May 1, 2019) - Brain tumours are the leading cause of non-accidental death in children in Canada, but little is known…

ArticleMay 01, 2019

CollaborationTreatment

Unraveling the circuitry behind brain cancer

Collaborative research group identifies new cancer-driving mechanisms in brain cancer stem cells, describes novel ways to overcome the limited effectiveness of standard therapy Dr. Graham MacLeod works at a lab bench at the University of…

ArticleApr 17, 2019

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