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TechnologyMultiple cancers

Finding the roots of cancer, ‘It’s a needle in a haystack’

Dr. Shimin Shuai OICR’s Dr. Shimin Shuai and Pan-Cancer Project collaborators identify new cancer-causing mutations in the non-coding region of the cancer genome Cancer begins with a ‘driver’ mutation – a DNA abnormality that may…

ArticleFeb 05, 2020

TechnologyMultiple cancers

TrackSig: Unlocking the history of cancer

Yulia Rubanova Toronto-based machine learning experts map the changes that lead to cancer, revealing opportunities for earlier diagnosis and new approaches to outmaneuver the disease A tumour is often made up of different cells, some…

ArticleFeb 05, 2020

TechnologyMultiple cancers

Unraveling the story behind the cancers we can’t explain

Dr. Philip Awadalla The Pan-Cancer Analysis of Whole Genomes Project has shown that despite cancer’s complexities, researchers are close to cataloguing all of the biological mechanisms that lead to the disease. Today, Nature released a…

ArticleFeb 05, 2020

TechnologyMultiple cancers

Discovering cancer’s vulnerabilities: The whole may be greater than the sum of its parts

OICR and Pan-Cancer Project researchers map key cancer pathways, signposting new directions for its diagnosis and treatment What works in a lab experiment doesn’t always work in the complex human body. But as technology advances,…

ArticleFeb 05, 2020

TechnologyMultiple cancers

New tumour-driving mutations discovered in the under-explored regions of the cancer genome

OICR researchers identify novel causes of cancer progression in the non-coding genome, opening new lines of investigation for several cancer types Toronto – (January 20, 2020) In an unprecedented pan-cancer analysis of whole genomes, researchers…

ArticleJan 20, 2020

Technology

New open-source software judges accuracy of algorithms that predict tumour evolution

Adriana Salcedo OICR-led international research group develops new open-source software to determine the accuracy of computational methods that can map the genetic history of tumour cells. A cancer patient’s tumour is often made up of…

ArticleJan 10, 2020

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