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Mathieu Lupien

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TechnologyBlood cancers

Researchers find 3-D structure of the genome is behind the self-renewing capabilities of blood stem cells

Drs. Mathieu Lupien and John Dick. OICR-funded researchers open a new path to discover drivers of chemotherapy resistance and cancer relapse Stem cells have the capability to self-renew and create other types of cells, but…

ArticleNov 30, 2020

TechnologyBreast cancer

New advances towards targeted therapies for triple negative breast cancer

OICR-supported researchers demonstrate new drug may eliminate triple negative breast cancer cells in certain patients, discover a new method to identify which patients will benefit Adapted from UHN’s Media Release. Triple negative breast cancer (TNBC)…

ArticleAug 25, 2020

TechnologyTreatment

New research unfolds the DNA “origami” behind brain cancers

Collaborative research group maps the three-dimensional genomic structure of glioblastoma and discovers a new therapeutic strategy to eliminate cells at the roots of these brain tumours Current treatment for glioblastoma – the most common type…

ArticleJul 17, 2019

TechnologyProstate cancer

Mutation in prostate tumours shown to change epigenetic identity, the make-up of DNA

Prostate cancer researchers have mapped the impact of an acquired mutation that alters epigenetic identity, the make-up of DNA, in about 50 per cent of patient tumour samples. The discovery also identifies a new opportunity…

ArticleAug 09, 2017

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Mathieu Lupien

Discover the latest news and insightsDiscover the latest news and insights

Tagged stories

Researchers find 3-D structure of the genome is behind the self-renewing capabilities of blood stem cells

New advances towards targeted therapies for triple negative breast cancer

New research unfolds the DNA “origami” behind brain cancers

Cancer solved together — in your inbox

Mutation in prostate tumours shown to change epigenetic identity, the make-up of DNA